Shakira, the leading nominee with five, performed the hit song with Sanz in typical gyrating fashion, her chest heaving and hips swaying to the reggaeton-inflected beat. Moments earlier, she was demure as she performed a low-key ballad.

"Thank you for this honor you've given me," Shakira, perhaps the evening's biggest star, said after winning the award, also thanking "the public and to Alejandro, who helped me with this song."

Cerati won two awards: best rock song for "Crimen" and best rock vocal album for "Ahi vamos."

Other winners included Mexican singer/accordion player Julieta Venegas, who was nominated for four awards. She won best alternative album for "Limon y sal" in the pre-televised awards ceremony.

Triple nominee Calle 13 picked up the short music video Grammy for its reggaeton song "Atrevete te, te!"

Under the Mexican regional award categories, Joan Sebastian took away the best banda album award for "Mas alla del sol."

The self-titled disc by Cafe de los Maestros won best tango album. The recording's Argentine producer, Gustavo Santaolalla, already won an Oscar this year for best original score on the movie "Brokeback Mountain" and recently composed music for the film "Babel."

This year, Madison Square Garden played host to the Latin Grammys, now in its sixth year. In the past, the show has alternated between Miami and Los Angeles.

Thursday's show was broadcast by Univision television for the second straight year. Ratings lagged in 2004 when the Latin Grammy Awards were broadcast in English by CBS. But the show attracted more than 5 million watchers in 2005 — its first year in Spanish — up from about 3.2 million in 2004, according to the ratings agency Nielsen Media Research.

Musicians from Puerto Rico earned 33 Latin Grammy nominations, including all the nominations for best urban music album and best salsa album.

The Latin Recording Academy: http://www.grammy.com/Latin/

Associated Press Writer Diego Santos contributed to this report.